The Ultimate Guide To https://www.ceesdekker.net
The Ultimate Guide To https://www.ceesdekker.net
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2009, discovery of a brand new phenotype for germs in slim nanofluidic slits; and 1st detection of regional protein constructions alongside DNA working with stable-point out nanopores
Our team reports bacterial cell division and is aiming to represent a ‘bottom up biology’ in synthetic cells that may autonomously divide. Our main interest lies in cell division, chromatin framework, and spatial Management.
, Groningen researchers current the outcome of their attempts to generate labs additional sustainable and supply guidelines for other labs.
Non-equilibrium folding of particular person DNA molecules recaptured nearly a thousand situations in the sound state nanopore
2010, designed a different way (‘wedging transfer’) to govern nanostructures; first report of DNA translocation via graphene nanopores; and recognized hybrid nanopores by directed insertion of α-hemolysin into stable-point out nanopores
SMC complexes can pass Actual physical roadblocks larger than their ring measurement, indicating a nontopological mechanism for DNA loop extrusion
We use nanofabricated microfluidic structures to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this evaluate the fundamental role of spatial confinement at the molecular and mobile amount. Our jobs include things like the subsequent:
Dynamic ParB–DNA interactions initiate and retain a partition condensate for bacterial chromosome segregation
What if, in lieu of employing standard major-down silicon electronics, transistors may be constructed from The underside up utilizing one natural molecules given that the switching factors? This concept, which became The premise of these days’s subject of molecular electronics, very first emerged during the 1970s.
There was cees dekker one difficulty however — we didn't notice any measurable electrical conduction from The only polymer molecules. We concluded that at The only-molecule stage, conducting polymers were being basically not such great conductors, which was instead disappointing. We Therefore broadened our check out to try to discover a lot more promising molecules.
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2001, discovery of solitary-electron transistors at area temperature based upon nanotubes; realization of initially logic circuits with carbon nanotube equipment; and discovery of the molecular structure of DNA restore enzymes with AFM
Developments in nanotechnology while in the nineties designed making Digital products from one molecules a probability. Cees Dekker recounts how his staff established a home-temperature transistor dependant on only one carbon nanotube.
Supercoiling-dependent DNA binding: quantitative modeling and applications to bulk and one-molecule experiments