ceesdekker.net - An Overview

ceesdekker.net - An Overview

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Employing solitary-molecule optical and AFM imaging and force-spectroscopy procedures, we search for to unravel the mechanistic areas of the composition and dynamics of chromosomes. Our exploration passions contain:

Human Rad51 filaments on double- and single-stranded DNA: correlating standard and irregular forms with recombination operate.

‘It had been merely a subject of picking up a ebook on mobile biology and starting to read through. I'd come from a entire world of extremely-higher vacuums, cryostats and quantum phenomena, and now I used to be Doing the job at space temperature with molecular biology kits.

Deposition and atomic drive microscopy of unique phthalocyanine polymers concerning nanofabricated electrodes

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever style and design in 2005. (nl)

Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

Numerous associated developments followed, in which our group set up distinct transistor variants for example solitary-electron transistors at area temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled several transistors into modest proof-of-principle electronic circuits.

Learning DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.

The rotors harness Power from the nanoscale drinking water and ion movement that is created by a static chemical or electrochemical likely gradient inside the nanopore, which are founded via a salt gradient or utilized voltage, respectively. These artificial nanoengines self-Arrange and function cees dekker autonomously in physiological conditions, suggesting tips on how to setting up energy-transducing motors at nanoscale interfaces.

There was a person issue even though — we did not observe any measurable electrical conduction from The only polymer molecules. We concluded that at The one-molecule stage, conducting polymers were being actually not this kind of fantastic conductors, which was fairly disappointing. We As a result broadened our look at to test to search out additional promising molecules.

An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes

1999, very first measurement of your wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof to get a new Luttinger description of interacting electrons in nanotubes

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It had been an exceptionally fascinating time, through which I received plenty of help from Delft College of Technological know-how, exactly where I used to be a professor at some time, And that i began many collaborations with molecular biologists. That served me learn a whole lot.’